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PIPELINE

APIs (PIPELINE)

S.No.PRODUCTCAS NUMBER

THERAPEUTIC USES

1Amphetamine 300-62-9Attention Deficit Hyperactivity Disorder (ADHD)
2Gabapentin Enacarbil478296-72-9Anti-epileptic
3Glycerol Phenylbutyrate611168-24-2Hyperammonemia Agent
4Prucalopride Succinate179474-85-2Chronic Idiopathic Constipation
5Naftifine Hydrochloride65473-14-5Anti-fungal
6Iloperidone133454-47-4Anti-psychotics
7Lomitapide Mesylate182431-12-5.Lipid-lowering agent
8Pitolisant Hydrochloride903576-44-3Narcolepsy
9Aliskerin173334-58-2Anti-hypertensive
10Flibanserin167933-07-5Anti-depressant
11Triheptanoin620-67-7Nutritive Agent
12Mechlorethamine Hydrochloride55-86-7Anti-cancer
13Suvorexant1030377-33-3Insomnia
14Idelalisib870281-82-6Anti-neoplastic agents
15Opicapone 923287-50-7Anti-parkinson's
16Peficitinib 944118-01-8Anti-cancer
17Diazepam439-14-5Anxiety
S.No. PRODUCT CAS NUMBER THERAPEUTIC USES
1. Amphetamine 300-62-9 Attention Deficit Hyperactivity Disorder (ADHD)
2. Gabapentin Enacarbil 478296-72-9 Anti-epileptic
3. Glycerol Phenylbutyrate 611168-24-2 Hyperammonemia Agent
4. Prucalopride Succinate 179474-85-2 Chronic Idiopathic Constipation
5. Naftifine Hydrochloride 65473-14-5 Anti-fungal
6. Iloperidone 133454-47-4 Anti-psychotics
7. Lomitapide Mesylate 182431-12-5. Lipid-lowering agent
8. Pitolisant Hydrochloride 903576-44-3 Narcolepsy
9. Aliskerin 173334-58-2 Anti-hypertensive
10. Flibanserin 167933-07-5 Anti-depressant
11. Triheptanoin 620-67-7 Nutritive Agent
12. Mechlorethamine Hydrochloride 55-86-7 Anti-cancer
13. Suvorexant 1030377-33-3 Insomnia
14. Idelalisib 870281-82-6 Anti-neoplastic agents
15. Opicapone 923287-50-7 Anti-parkinson's
16. Peficitinib 944118-01-8 Anti-cancer
17. Diazepam 439-14-5 Anxiety

Intermediates (PIPELINE)

S.No.PRODUCTCAS NUMBER

API

16,7-Dimethoxy-4-quinolinol13425-93-9Cabozantinib S-Malate
24-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline190728-25-7Cabozantinib S-Malate
3Methyl 1-[(4-fluorophenyl)carbamoyl]cyclopropane Carboxylate1345847-71-3Cabozantinib S-Malate
41-[(4-fluorophenyl)Amino carbonyl]cyclopropane carboxylic acid849217-48-7Cabozantinib S-Malate
56,7-Dimethoxy-4-(4-nitrophenoxy)quinolone190728-24Ponatinib Hydrochloride
61-methyl-4-nitro-2-(trifluoromethyl) benzene89976-12-5Ponatinib Hydrochloride
71-methyl-4-[4-nitro-2-(trifluoromethyl)benzyl] piperazine 694499-24-6Ponatinib Hydrochloride
83-Iodo-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3 (trifluoromethyl)phenyl] Benzamide2097674-16-1Ponatinib Hydrochloride
93-BromoImidazo [1,2-b]pyridazine18087-73-5Ponatinib Hydrochloride
104-[(4-Methylpiperazin-1-yl) methyl]-3(trifluoromethyl)aniline694499-26-8Ponatinib Hydrochloride
114-chloropyrrolo[2,3-d]pyrimidine 3680-69-1Ruxolitinib Phosphate
121-(1-Ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole1029716-44-6Ruxolitinib Phosphate
132-chloro-5-nitropyridine4548-45-2Ruxolitinib Phosphate
143-bromo-4-methylbenzoic acid7697-26-9Sonidegib Phosphate
15Cis 2,6-dimethyl-4-(5-nitropyridin-2-yl)morpholine956699-05-1Sonidegib Phosphate
163-amino-6-(cis-2,6-dimethylmorpholin-4-yl)pyridine956699-06-2Sonidegib Phosphate
173-Bromo-N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridin-3-yl]-2-methylbenzamide1221721-86-3Sonidegib Phosphate
182-Methyl-4'-(trifluoromethoxy)biphenyl-3-carboxylic acid1221722-10-6Sonidegib Phosphate
192-fluoro-3-nitrotoluene437-86-5Dabrafenib Mesylate
202-fluoro-3-nitrobenzoic acid317-46-4Dabrafenib Mesylate
212-chloro-4-methylpyrimidine13036-57-2Dabrafenib Mesylate
22Methyl 3-[[(2,6-difluorophenyl)sulfonyl]amino]-2-fluorobenzoate1195768-19-4Dabrafenib Mesylate
232-chloro-5-nitroaniline6283-25-6Vismodegib
241-chloro-2-iodo-4-nitrobenzene74534-15-9Vismodegib
252-(2-chloro-5-nitrophenyl)pyridine879088-40-1Vismodegib
262-chloro-4-(methylsulfonyl)benzoic acid53250-83-2Vismodegib
274-Chloro-3-pyridin-2-ylaniline879088-41-2Vismodegib
285-bromo-7-azaindole183208-35-7Vemurafenib
295-(4-chlorophenyl)pyrrolo[2,3-b]pyridine918516-27-5Vemurafenib
308-ethoxy-8-oxooctanoic acid14113-01-0Vorinostat
S.No. PRODUCT CAS NUMBER Therapeutic Category THERAPEUTIC USES
1. 6,7-Dimethoxy-4-quinolinol 13425-93-9 Cabozantinib S-Malate
2. 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline 190728-25-7
3. Methyl 1-[(4-fluorophenyl)carbamoyl]cyclopropane Carboxylate 1345847-71-3
4. 1-[(4-fluorophenyl)Amino carbonyl]cyclopropane carboxylic acid 849217-48-7
5. 6,7-Dimethoxy-4-(4-nitrophenoxy)quinolone 190728-24 Ponatinib Hydrochloride
6. 1-methyl-4-nitro-2-(trifluoromethyl) benzene 89976-12-5
7. 1-methyl-4-[4-nitro-2-(trifluoromethyl)benzyl] piperazine 694499-24-6
8. 3-Iodo-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3 (trifluoromethyl)phenyl] Benzamide 2097674-16-1
9. 3-BromoImidazo [1,2-b]pyridazine 18087-73-5
10. 4-[(4-Methylpiperazin-1-yl) methyl]-3(trifluoromethyl)aniline 694499-26-8
11. 4-chloropyrrolo[2,3-d]pyrimidine 3680-69-1 Ruxolitinib Phosphate
12. "1-(1-Ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxa
borolan-2-yl)-1H-pyrazole"		 1029716-44-6
13. 2-chloro-5-nitropyridine 4548-45-2 Sonidegib Phosphate
14. 3-bromo-4-methylbenzoic acid 7697-26-9
15. Cis 2,6-dimethyl-4-(5-nitropyridin-2-yl)morpholine 956699-05-1
16. 3-amino-6-(cis-2,6-dimethylmorpholin-4-yl)pyridine 956699-06-2
17. 3-Bromo-N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridin-3-yl]-2-methylbenzamide 1221721-86-3
18. 2-Methyl-4'-(trifluoromethoxy)biphenyl-3-carboxylic acid 1221722-10-6
19. 2-fluoro-3-nitrotoluene 437-86-5 Dabrafenib Mesylate
20. 2-fluoro-3-nitrobenzoic acid 317-46-4
21. 2-chloro-4-methylpyrimidine 13036-57-2
22. Methyl 3-[[(2,6-difluorophenyl)sulfonyl]amino]-2-fluorobenzoate 1195768-19-4
23. 2-chloro-5-nitroaniline 6283-25-6 Vismodegib
24. 1-chloro-2-iodo-4-nitrobenzene 74534-15-9
25. 2-(2-chloro-5-nitrophenyl)pyridine 879088-40-1
26. 2-chloro-4-(methylsulfonyl)benzoic acid 53250-83-2
27. 4-Chloro-3-pyridin-2-ylaniline 879088-41-2
28. 5-bromo-7-azaindole 183208-35-7 Vemurafenib
29. 5-(4-chlorophenyl)pyrrolo[2,3-b]pyridine 918516-27-5
30. 8-ethoxy-8-oxooctanoic acid 14113-01-0 Vorinostat

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